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Amaryl (Glimepiride) – oral drug for treating type 2 diabetes mellitus that cannot be controlled by diet and exercise alone

Buy AmarylGeneral information

Amaryl is used in patients with type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus) that cannot be controlled by diet and exercise alone. Generic for Amaryl is glimepiride. Glimepiride is marketed as Amaryl by Sanofi-Aventis. Taking Amaryl medication does not cancel compliance with the diet and exercise recommendations. Amaryl can be taken either alone or in combination with other antidiabetic drugs.

Buy Amaryl (Glimepiride)

How Amaryl Works

Amaryl refers to the class of sulfonylurea drugs that help manage diabetes by making the pancreas beta cells release more insulin and by increasing the activity of insulin receptors. Amaryl is generally considered to be second-generation sulfonylurea, and sometimes is classified as third-generation sulfonylurea due to its extremely high effectiveness. In comparison with other secondary sulfonylureas, Amaryl has a very small risk of hypoglycaemia. Besides, it does not suppress the secretion of glucagon in response to hypoglycaemia.

How Should I Use Amaryl

Carefully follow the instructions given by your doctor concerning the Amaryl treatment schedule. Whatever Amaryl mg dose you’ve been prescribed, remember the following:

  • Amaryl is taken with breakfast or your first main meal (if not prescribed differently).
  • Amaryl should be taken the same time each day.
  • Continue taking Amaryl even if your start feeling better.

You can buy Amaryl in the following forms:

  • Amaryl 1 mg
  • Amaryl 2 mg
  • Amaryl 4 mg

Strict compliance with the prescribed Amaryl dosage regimen is vital. As Amaryl medication controls your blood sugar levels, make sure you never miss your Amaryl mg dose and never overdose on Amaryl.

What if I miss a dose? If you miss your Amaryl mg dose, you can take it as soon as you remember. If it’s almost time for the next dose, skip the missed Amaryl mg dose and continue treatment according to the regular schedule. Never take a doubled Amaryl dose.

What happens if take a bigger dose? Amaryl overdose causes hypoglycemia with such symptoms as seizures, weakness, confusion, fainting, etc. If you overdose on Amaryl, seek emergency medical assistance immediately.

How should I store Amaryl? Amaryl should be stored in a place safe from children and pets at the temperature range of 59-860 F (15-300 C), away from humidity, moisture, and light. Never store your Amaryl medication in a bathroom.

Where to Buy Amaryl

You can purchase Amaryl either online or in a local drugstore in case you have a prescription from your doctor. Lately, it has become especially convenient to order Amaryl online in terms of availability, prescription, time, price, and delivery. Online drugstores like ours are a good place to find cheap Amaryl or purchase Amaryl at discount. Here, you can find attractive offers for Amaryl 1 mg, Amaryl 2 mg, and Amaryl 4 mg.

Safety – learn before using

Compliance with the prescribed Amaryl dosage regimen is not the only thing that you need to pay attention to. Before you buy Amaryl and start your treatment, study carefully all the safety information. It includes conditions and diseases that will not allow you to start Amaryl treatment, as well as medical conditions and medications that may interact with Amaryl.

Contraindications

If you have any of the below listed medical conditions or diseases, Amaryl diabetes treatment is contraindicated to you:

  • Hypersensitivity to any component of Amaryl.
  • Serious health problems caused by diabetes (e.g., diabetic ketoacidosis, diabetic coma, etc.).
  • Moderate and severe burns.
  • Acidosis (high blood acid levels).
  • Current treatment with bosentan.

Alerting Medical Conditions

Some medical conditions may interact with Amaryl causing health problems. If you have any of the following, consult your doctor before you purchase Amaryl and start treatment:

  • Current or planned pregnancy, lactation (breastfeeding).
  • Current treatment with other medications, current intake of herbal preparations and food supplements.
  • Allergic reactions to foods, medicines, and other substances.
  • Severe allergic reactions (rash, breathing problems, hives, dizziness, rash, etc.) to sulfonamide drugs (celecoxib, acetazolamide, etc), certain diuretics (hydrochlorothiazide, etc.), and also glipizide, valdecoxib, zonisamide, probenecid, and sulfamethoxazole.
  • History of stroke.
  • History of heart, liver, kidney, stomach, bowel, or thyroid problems.
  • History of certain hormonal problems (adrenal and pituitary problems, SIADH, etc.).
  • Low blood sodium levels or high blood acid levels.
  • Type 1 diabetes mellitus.
  • High fever, severe infection, severe diarrhea, severe injury, and general poor state of health.
  • Alcohol consumption.
  • Malnutrition.
  • Planned surgery.

Interaction with Other Drugs

Before you buy Amaryl online or in a drugstore, carefully study the list of medications that may interact with Amaryl. If you are currently taking or planning to take any of these drugs, do not buy Amaryl until you consult your doctor concerning the combination of Amaryl with the following:

  • Drugs decreasing both their own and Amaryl effectiveness:
    bosentan (may also cause problems with liver).
  • Drugs increasing the risk of hypoglycemia:
    beta-blockers, angiotensin-converting enzyme inhibitors, anticoagulants, azole antifungals, chloramphenicol, clofibrate, clofibrate, fenfluramine insulin, metformin, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory drugs, phenylbutazone, probenecid, quinolone antibiotics, salicylates, sulfonamides.
  • Drugs decreasing the effectiveness of Amaryl, which leads to hyperglycaemia:
    calcium channel blockers, corticosteroids, decongestants, diazoxide, diuretics, estrogens, hormonal contraceptives, isoniazid, niacin, phenothiazines, phenytoin, rifamycins, sympathomimetics, thyroid supplements.
  • Drugs either increasing or decreasing blood sugar levels:
    gemfibrozil.

Possible Side Effects

Amaryl may cause some side effects. This does not mean that you will necessarily experience all or some of them, as most patients experience either no or only minor Amaryl side effects. Nevertheless, you need to be fully aware of both minor and severe Amaryl side effects. If some of the following common minor Amaryl side effects become bothersome or persistent, contact your doctor.

Common Minor Amaryl Side Effects:

  • Nausea.

Severe Amaryl Side Effects:

  • Severe allergic reactions – rash, swelling of the mouth, lips, tongue, or face, breathing difficulties, etc.
  • Vision problems – blurred vision, poor eyesight, etc.
  • Hypoglycemia symptoms – headache, sweating, increased hunger, dizziness, tremors, fast heartbeat, etc.
  • Unusual tiredness and weakness.
  • Dark urine, jaundice (eyes/skin yellowing).
  • Confusion, fever, chills, persistent sore throat.
  • Unusual bruising or bleeding.

If you experience any of these severe Amaryl side effects, seek emergency medical assistance immediately. What is more, contact your doctor as soon as possible if Amaryl treatment worsens or does not improve your diabetes.

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