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Glucophage (Metformin) – oral drug for treating type 2 diabetes mellitus

Buy GlucophageGeneral information

Glucophage and Glucophage XR (extended release form) are prescribed for treating type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus). Its generic name is metformin. Metformin is now the most commonly prescribed anti-diabetic drug in the world. Glucophage and Glucophage XR are used along with special diet and exercise program. Often, Glucophage is prescribed to be taken in combination with other medications.

Buy Glucophage (Metformin)

How Glucophage Works

Glucophage refers to the biguanide class of drugs. It suppressed the production of glucose by the liver and decreases the absorption of glucose in the intestines. What is more, it increases sensitivity to insulin produced by your body. These Glucophage effects help to keep the blood sugar levels normal.

Apart from gaining control over diabetes, many patients experience weight loss with Glucophage. Owing to Glucophage effects on weight, it is most commonly prescribed to overweight and obese diabetic patients. As the body of people with type 2 diabetes does not produce enough insulin, they are prescribed Glucophage or Glucophage XR so that their body could process glucose with a smaller amount of insulin. Patients are losing weight with Glucophage because reduced release of insulin decreases the feeling of hunger and fat production in the liver. For these Glucophage effects, some people are willing to take Glucophage for weight loss alone. Nevertheless, it is necessary to know that weight loss with Glucophage is not the only effect that you will experience. There are a number of Glucophage side effects that you might have. That is why you need to have Glucophage prescribed by the doctor who knows whether you really need this medication or not.

Since 1980s, it has been proposed to use Glucophage for polycystic ovary syndrome (PCOS) treatment, which is associated with insulin resistance. Unfortunately, a number of clinical trials showed that the effectiveness of Glucophage for PCOS is not higher than the one of placebo. Glucophage for polycystic ovary syndrome can be effective as the first-line treatment only in women with glucose intolerance.

At the same time, much better effects are revealed in the researches concerning Glucophage and pregnancy in women with PCOS. It is proved to improve ovulation and pregnancy rates, and also to reduce the risk of first-trimester miscarriages. Here, no serious Glucophage side effects were observed except for jaundice in some babies.

How Should I Use Glucophage

You should take the medication according to the Glucophage prescription provided by your doctor. To learn exact Glucophage dosing instructions, check the medicine label. These are the general instructions that you need to know and use:

  • Glucophage is taken by mouth with food.
  • Glucophage should be taken regularly according to the schedule to get the maximum effect from the treatment.
  • Glucophage is better to take the same time each day.
  • Glucophage treatment should not be stopped even if you start feeling better.
  • Try not to miss any Glucophage mg dose.

You need to meticulously follow the Glucophage prescription and take the specific Glucophage mg dose recommended by your doctor.

You can buy Glucophage in the following forms:

  • Glucophage 500 mg
  • Glucophage 800 mg
  • Glucophage 1000 mg

If you are prescribed to take the extended release form of Glucophage, you can buy it in the following forms:

  • Glucophage XR 500 mg
  • Glucophage XR 750 mg

You should not change the prescribed Glucophage dosing and the regimen on your own. If you do this, you are facing the risk of negative Glucophage effects.

What if I miss a dose? If you missed your Glucophage mg dose, you need to take it as soon as you remember in case you are ready to have a meal. If it’s almost time for the next scheduled dose, you should skip the missed dose. Never take 2 doses at once.

What happens if take a bigger dose? The Glucophage overdose may trigger lactic acidosis. Its symptoms include weakness, sleepiness, pain in muscles, stomach ache, slow heart rate, shortness of breath, fainting etc. If you overdose on Glucophage, you need to seek emergency medical assistance immediately.

How should I store Glucophage? Glucophage should be stored in a safe place at the temperature range of 68-770 F (20-250 C), away from humidity and moisture.

Where to Buy Glucophage

With a Glucophage prescription, you can buy Glucophage 500 mg, Glucophage 800 mg, Glucophage 100 mg, Glucophage XR 500 mg, and Glucophage XR 750 mg in a drugstore. For more convenience, you can buy Glucophage online in a reliable online store like ours. On the Internet, you can often be offered to buy Glucophage without prescription. Online drugstores are a good place to find cheap Glucophage.

Safety – learn before using

There are a number of cases when Glucophage treatment cannot be prescribed, as it may have negative effects on your health. You need to be aware of the contraindications, alerting medical conditions, and lists of drugs that may interact with Glucophage before you buy this medication. In such a way, you will avoid the risk of serious Glucophage side effects and other undesirable conditions.

Contraindications

The following is the list of medical conditions that do not allow you to undergo Glucophage treatment. If you have any of these, inform your doctor or health provider and do not start taking Glucophage:

  • Hypersensitivity to any components of Glucophage.
  • Congestive heart failure that requires medical treatment.
  • Problems with liver or kidneys.
  • Recent history of a stroke, heart attack, or current shock.
  • Severe infection.
  • Low blood oxygen levels.
  • High blood ketone or acid levels.
  • Over 80 years old and no kidney function test carried out.
  • Planned surgery or lab procedures.

Alerting Medical Conditions

These are the medical conditions that may interact with Glucophage. In order to be confident in the Glucophage treatment effectiveness and avoid any negative Glucophage effects, please consult with your doctor if you have any of the following:

  • Pregnancy (current or planning) and lactation (breast-feeding).
  • Any allergic reactions to medicines, food, and other substances.
  • Current treatment with other medications, intake of food supplements and herbal preparations.
  • History of problems with heart, lungs, thyroid, stomach and bowel, adrenal cortex and pituitary gland, or lactic acidosis.
  • Fever, infection, moderate and severe burns, recent injury.
  • Planned surgery or lab procedures.
  • Vomiting, diarrhea.
  • Low blood calcium or vitamin B12 levels, anemia.
  • Poor health and malnutrition.
  • History of alcohol abuse or current alcohol consumption.
  • Current beta-blocker treatment.

Interaction with Other Drugs

Some medications when taken in combination with Glucophage may interact with the latter. This may lead to the changes in the effectiveness of the treatment by either medication and to serious adverse events. These are the groups of drugs that may interact with Glucophage:

  • Drugs increasing the risk of Glucophage side effects:
    amiloride, cimetidine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin.
  • Drugs either increasing or decreasing blood sugar levels:
    calcium channel blockers, corticosteroids, diuretics, estrogen, hormonal contraceptives, insulin, isoniazid, nicotinic acid, phenothiazine, phenytoin, sulfonylurea, sympathomimetics, thyroid hormones.

If you are taking or planning to take any of these drugs, please consult with your doctor concerning the possibility of Glucophage treatment.

Possible Side Effects

When undergoing Glucophage treatment, most patients experience no or minor Glucophage side effects. Still, you need to be aware of all minor and severe side effects of this medication.

Common Minor Glucophage Side Effects:

  • Nausea, vomiting.
  • Diarrhea, gas, stomach upset, indigestion.
  • Headache, muscle pain, weakness.
  • Temporary metallic taste

Severe Glucophage Side Effects:

  • Severe allergic reactions – swelling of the mouth and face, rash, breathing difficulties, etc.
  • Chest pain and discomfort, difficult breathing.
  • Fever, chills, persistent sore throat.
  • Unusual drowsiness, tiredness, weakness.
  • Muscle pain, stomach pain.
  • Slow or irregular heartbeat.

Seek emergency medical attention if you have any of the severe Glucophage side effects. Contact your doctor if you are not responding to Glucophage treatment or your medical condition gets worse.

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